Objective: Using [11C]MK-6884, an M4 positive allosteric modulator radioligand, this study evaluated M4 receptor occupancy (RO) of CVL-231 in the striatum of nonhuman primates as a function of CVL-231 dose and plasma concentration.
Objective: Using [11C]MK-6884, an M4 positive allosteric modulator radioligand, this study evaluated M4 receptor occupancy (RO) of CVL-231 in the striatum of nonhuman primates as a function of CVL-231 dose and plasma concentration.
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