Objective: To investigate the effects of systemic subcutaneous (SC) administration of 2 different test compounds (TC) – a full (CV-0000042) compared with a partial (CV-0000071) M4 receptor agonist – at 2 doses each on amphetamine-induced brain activity in anesthetized Sprague-Dawley rats (Crl:CD(SD)) using relative cerebral blood volume (rCBV) functional MRI (fMRI) readout